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Det finnes lite dokumentasjon for effekt av kodein, tramadol, dekstropropoksyfen og pentazocin mot kroniske smerter. Statens legemiddelverk anbefaler samme retningslinjer for alle opioide analgetika ved behandling av langvarige smerter (six): Pasienten skal informeres grundig om virkninger og bivirkninger, spesielt om abstinens, avhengighet og misb
) som gir sterke smerter som er vanskelig å behandle. Den andre gruppen er personer med «halvakutte» smerter der det er reell fare for at tilstanden skal bli kronisk. Dersom det foreligger tilstander der smerteårsaken ikke kan behandles skal selvsagt ikke pasienten til noen smerteklinikk for behandling. Doktorgrad om hodepineBetennelsen forårs
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